Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF)
Dysregulation of VEGF-A bioavailability has been implicated in the development of lung injury/fibrosis, exemplified by Idiopathic Pulmonary Fibrosis (IPF). VEGF-A is a target of the hypoxic response via its translational regulation by HIF-1α. The role of hypoxia and hyperoxia in the development and...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
BioMed Central
2018
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/50178/ |