Physical activity pre- and post-dementia: English Longitudinal Study of Ageing

Background: To inform public health interventions, further investigation is needed to identify: (1) frequency/intensity of everyday physical activity (PA) needed to reduce dementia risk; (2) whether post-diagnosis reduction in PA is associated with cognitive outcomes. Methods: Data from 11,391 men a...

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Main Authors: Soni, Mira, Orrell, Martin, Bandelow, Stephan, Steptoe, Andrew, Rafnsson, Snorri, d'Orsi, Eleonora, Xavier, Andre, Hogervorst, Eef
Format: Article
Published: Taylor & Francis 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/50143/
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author Soni, Mira
Orrell, Martin
Bandelow, Stephan
Steptoe, Andrew
Rafnsson, Snorri
d'Orsi, Eleonora
Xavier, Andre
Hogervorst, Eef
author_facet Soni, Mira
Orrell, Martin
Bandelow, Stephan
Steptoe, Andrew
Rafnsson, Snorri
d'Orsi, Eleonora
Xavier, Andre
Hogervorst, Eef
author_sort Soni, Mira
building Nottingham Research Data Repository
collection Online Access
description Background: To inform public health interventions, further investigation is needed to identify: (1) frequency/intensity of everyday physical activity (PA) needed to reduce dementia risk; (2) whether post-diagnosis reduction in PA is associated with cognitive outcomes. Methods: Data from 11,391 men and women (aged ≥50) were obtained in the English Longitudinal Study of Ageing. Assessments were at baseline (2002-2003) and biannual follow-ups (2004-2013). Results: Older adults who carried out moderate to vigorous activity at least once per week had a 34%-50% lower risk for cognitive decline and dementia over an 8-10 year follow-up period. From pre- to post-diagnosis, those that decreased PA levels had a larger decrease in immediate recall score, compared to those that maintained or increased PA levels (adjusted for changes in physical function). Conclusion: These findings provide a guideline for everyday PA levels needed to reduce risk for dementia. Reduction in PA after diagnosis was also associated with accelerated cognitive decline.
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spelling nottingham-501432020-05-04T19:12:49Z https://eprints.nottingham.ac.uk/50143/ Physical activity pre- and post-dementia: English Longitudinal Study of Ageing Soni, Mira Orrell, Martin Bandelow, Stephan Steptoe, Andrew Rafnsson, Snorri d'Orsi, Eleonora Xavier, Andre Hogervorst, Eef Background: To inform public health interventions, further investigation is needed to identify: (1) frequency/intensity of everyday physical activity (PA) needed to reduce dementia risk; (2) whether post-diagnosis reduction in PA is associated with cognitive outcomes. Methods: Data from 11,391 men and women (aged ≥50) were obtained in the English Longitudinal Study of Ageing. Assessments were at baseline (2002-2003) and biannual follow-ups (2004-2013). Results: Older adults who carried out moderate to vigorous activity at least once per week had a 34%-50% lower risk for cognitive decline and dementia over an 8-10 year follow-up period. From pre- to post-diagnosis, those that decreased PA levels had a larger decrease in immediate recall score, compared to those that maintained or increased PA levels (adjusted for changes in physical function). Conclusion: These findings provide a guideline for everyday PA levels needed to reduce risk for dementia. Reduction in PA after diagnosis was also associated with accelerated cognitive decline. Taylor & Francis 2017-10-17 Article PeerReviewed Soni, Mira, Orrell, Martin, Bandelow, Stephan, Steptoe, Andrew, Rafnsson, Snorri, d'Orsi, Eleonora, Xavier, Andre and Hogervorst, Eef (2017) Physical activity pre- and post-dementia: English Longitudinal Study of Ageing. Aging and Mental Health . ISSN 1364-6915 Alzheimer’s Disease Other Dementias Epidemiology (Dementia) Physical Activity Cognitive Functioning https://doi.org/10.1080/13607863.2017.1390731 doi:10.1080/13607863.2017.1390731 doi:10.1080/13607863.2017.1390731
spellingShingle Alzheimer’s Disease
Other Dementias
Epidemiology (Dementia)
Physical Activity
Cognitive Functioning
Soni, Mira
Orrell, Martin
Bandelow, Stephan
Steptoe, Andrew
Rafnsson, Snorri
d'Orsi, Eleonora
Xavier, Andre
Hogervorst, Eef
Physical activity pre- and post-dementia: English Longitudinal Study of Ageing
title Physical activity pre- and post-dementia: English Longitudinal Study of Ageing
title_full Physical activity pre- and post-dementia: English Longitudinal Study of Ageing
title_fullStr Physical activity pre- and post-dementia: English Longitudinal Study of Ageing
title_full_unstemmed Physical activity pre- and post-dementia: English Longitudinal Study of Ageing
title_short Physical activity pre- and post-dementia: English Longitudinal Study of Ageing
title_sort physical activity pre- and post-dementia: english longitudinal study of ageing
topic Alzheimer’s Disease
Other Dementias
Epidemiology (Dementia)
Physical Activity
Cognitive Functioning
url https://eprints.nottingham.ac.uk/50143/
https://eprints.nottingham.ac.uk/50143/
https://eprints.nottingham.ac.uk/50143/