Transient accumulation of 5-carboxylcytosine indicates involvement of active demethylation in lineage specification of neural stem cells

QR Code

Transient accumulation of 5-carboxylcytosine indicates involvement of active demethylation in lineage specification of neural stem cells

5-Methylcytosine (5mC) is an epigenetic modification involved in regulation of gene activity during differentiation. Tet dioxygenases oxidize 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). Both 5fC and 5caC can be excised from DNA by thymine-DNA glycosy...

Full description

Bibliographic Details
Main Authors:	Wheldon, Lee M., Abakir, Abdulkadir, Ferjentsik, Zoltan, Dudnakova, Tatiana, Strohbuecker, Stephanie, Christie, Denise, Dai, Nan, Guan, Shengxi, Foster, Jeremy M., Corrêa, Ivan R, Loose, Matthew, Dixon, James E., Sottile, Virginie, Johnson, Andrew D., Ruzov, Alexey
Format:	Article
Published:	Elsevier 2014
Online Access:	https://eprints.nottingham.ac.uk/49914/

Similar Items

5-Carboxylcytosine is localized to euchromatic regions in the nuclei of follicular cells in axolotl ovary
by: Alioui, Anthony, et al.
Published: (2012)

Dynamics of 5-carboxylcytosine during hepatic differentiation: potential general role for active demethylation by DNA repair in lineage specification
by: Lewis, Lara C., et al.
Published: (2017)

Medulloblastoma and ependymoma cells display levels of 5-carboxylcytosine and elevated TET1 expression
by: Ramsawhook, Ashley, et al.
Published: (2017)

Detection of modified forms of cytosine using sensitive immunohistochemistry
by: Abakir, Abdulkadir, et al.
Published: (2016)

Semi-quantitative immunohistochemical detection of 5-hydroxymethyl-cytosine reveals conservation of its tissue distribution between amphibians and mammals
by: Almeida, Rimple D., et al.
Published: (2012)

Expression of a SOX1 overlapping transcript in neural differentiation and cancer models
by: Azaz, Ahmad, et al.
Published: (2017)

5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development
by: Almeida, Rimple D., et al.
Published: (2012)

Towards quantitative molecular mapping of cells by Raman microscopy: using AFM for decoupling molecular concentration and cell topography
by: Boitor, Radu, et al.
Published: (2016)

Wilms' Tumor protein 1 and enzymatic oxidation of 5-methylcytosine in brain tumors: potential perspectives
by: Ramsawhook, Ashley, et al.
Published: (2018)

Developmental functions of the dynamic DNA methylome and hydroxymethylome in the mouse and zebrafish: similarities and differences
by: Jessop, Peter, et al.
Published: (2018)

Immunostaining for DNA modifications: computational analysis of confocal images
by: Ramsawhook, Ashley, et al.
Published: (2017)

Stepwise evolution of Elk-1 in early deuterostomes
by: Saxton, Janice, et al.
Published: (2016)

Differences in the pattern and regulation of mineral deposition in human cell lines of osteogenic and non-osteogenic origin
by: Rashidi, Hassan, et al.
Published: (2011)

Tracking Cells and Their Lineages Via Labeled Random Finite Sets
by: Nguyen, Tran Thien Dat, et al.
Published: (2021)

Early Connections: Reflections on the canonical lineage of Southeast Asian Temples
by: Datta, Sambit, et al.
Published: (2011)

Multi-lineage differentiation of mesenchymal stem cells - To Wnt, or not Wnt
by: Visweswaran, Malini, et al.
Published: (2015)

Primordial germ cells: the first cell lineage or the last cells standing?
by: Johnson, Andrew D., et al.
Published: (2015)

Specification and epigenetic resetting of the pig germline exhibit conservation with the human lineage
by: Zhu, Qifan
Published: (2021)

Biological cell tracking and lineage inference via random finite sets
by: Nguyen, Tran Thien Dat, et al.
Published: (2021)

On-line Tracking of Cells and Their Lineage from Time Lapse Video Data
by: Dat Nguyen, T., et al.
Published: (2018)

Cells of Epithelial Lineage Are Detectable In Peripheral Blood and Are Increased in Lung Transplantation
by: May, L.A., et al.
Published: (2009)

Perspectives on ancestral lineages and genetic markers of Malay population in Peninsular Malaysia
by: Shalini Parthipan,, et al.
Published: (2022)

Celebrating the generation of architectural ideas: tracing the lineage of Southeast Asian temples
by: Beynon, D., et al.
Published: (2005)

Lineage diversification of pigeon paramyxovirus effect re-emergence potential in chickens
by: Yee, Ling Chong, et al.
Published: (2014)

Differentiation of skeletal muscle-derived stem cells into beta pancreatic lineage
by: Yeo, Wendy Wai Yeng
Published: (2015)

Exposure to the ROCK inhibitor fasudil promotes gliogenesis of neural stem cells in vitro
by: Nizamudeen, Zubair Ahmed, et al.
Published: (2018)

Exposure to the ROCK inhibitor fasudil promotes gliogenesis of neural stem cells in vitro
by: Nizamudeen, Zubair Ahmed, et al.
Published: (2018)

Transcription factor lineages in plant-pathogenic fungi, connecting diversity with fungal virulence
by: John, Evan, et al.
Published: (2022)

Early lineage switch from T-acute lymphoblastic leukaemia to common B-all.
by: Hafiza, A, et al.
Published: (2011)

Tracking niche variation over millennial timescales in sympatric killer whale lineages
by: Foote, A., et al.
Published: (2013)

Genetic Lineages of Community-Associated Methicillin-Resistant Staphylococcus aureus in Kuwait Hospitals
by: Udo, Edet, et al.
Published: (2008)

Nucleolytic Cleavage of the Mixed Lineage Leukemia Breakpoint Cluster Region during Apoptosis
by: Sim, S.P, et al.
Published: (2001)

Ecological and evolutionary diversification of sulphated polysaccharides in diverse photosynthetic lineages: a review
by: Lee, Wei Kang, et al.
Published: (2021)

Primary Airway Epithelial Cells That Are Conditionally Reprogrammed Maintain Lineage, Phenotypic And Functional Characteristics
by: Kicic, Anthony, et al.
Published: (2016)

Bone marrow-derived mesenchymal cell differentiation toward myogenic lineages: Facts and perspectives
by: Galli, D., et al.
Published: (2014)

Evolutionary lineage of naked harmful dinoflagellates, karlodinium/karenia/takayama/gyrodinium complex (Dinophyceae)
by: Chow, Luan Jia
Published: (2011)

Characterisation of Myeloid, Lymphiod and Erythroid Cell Lineages in Myelodysplastics Syndrome Using Flow Cytometry
by: Broojerdi, Mohadese Hashem
Published: (2011)

Phylogenetic analysis revealed first report of Eleutheronema rhadinum lineage in the coastal waters of Malaysia
by: Atikah, N.W., et al.
Published: (2020)

Cells of Epithelial Lineage Are Present in Blood, Engraft the Bronchial Epithelium, and Are Increased in Human Lung Transplantation
by: May, L.A., et al.
Published: (2009)

Conditionally reprogrammed primary airway epithelial cells successfully maintain lineage, phenotypic and functional characteristics
by: Martinovich, K., et al.
Published: (2015)