Comparison of gene transfection and cytotoxicity mechanisms of linear poly(amidoamine) and branched poly(ethyleneimine) polyplexes
Purpose: This study aimed to further explore the mechanisms behind the ability of certain linear polyamidoamines (PAAs) to transfect cells with minimal cytotoxicity. Methods: The transfection efficiency of DNA complexed with a PAA of a molecular weight over 10 kDa or 25 kDa branched polyethyleneim...
| Main Authors: | , , , , |
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| Format: | Article |
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Springer
2018
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/49838/ |