Citrullinated vimentin presented on MHC-II in tumor cells is a target for CD4+ T-cell-mediated antitumor immunity

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Citrullinated vimentin presented on MHC-II in tumor cells is a target for CD4+ T-cell-mediated antitumor immunity

Stressful conditions in the harsh tumor microenvironment induce autophagy in cancer cells as a mechanism to promote their survival. However, autophagy also causes post-translational modification of proteins that are recognized by the immune system. In particular, modified self-antigens can trigger C...

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Bibliographic Details
Main Authors:	Brentville, Victoria A., Metheringham, Rachael L., Gunn, Barbara, Symonds, Peter, Daniels, Ian, Gijon, Mohamed, Cook, Katherine, Xue, Wei, Durrant, Lindy
Format:	Article
Published:	American Association for Cancer Research 2016
Online Access:	https://eprints.nottingham.ac.uk/49781/

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