Dendritic spine dynamics regulate the long-term stability of synaptic plasticity

Long-term synaptic plasticity requires postsynaptic influx of Ca²⁺ and is accompanied by changes in dendritic spine size. Unless Ca²⁺ influx mechanisms and spine volume scale proportionally, changes in spine size will modify spine Ca²⁺ concentrations during subsequent synaptic activation. We show th...

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Bibliographic Details
Main Authors: O'Donnell, Cian, Nolan, Matthew F., van Rossum, Mark C.W.
Format: Article
Published: Society for Neuroscience 2011
Online Access:https://eprints.nottingham.ac.uk/49642/