Simplified footprint-free Cas9/CRISPR editing of cardiac-associated genes in human pluripotent stem cells
Modelling disease with hPSCs is hindered because the impact on cell phenotype from genetic variability between individuals can be greater than from the pathogenic mutation. While ‘footprint-free’ Cas9/CRISPR editing solves this issue, existing approaches are inefficient or lengthy. Here, a simplifie...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Mary Ann Liebert
2018
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/49543/ |