Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance
The pattern of metabolic reprogramming in chronic hypoxia shares similarities with that following myocardial infarction or hypertrophy, however the response of the chronically hypoxic heart to subsequent acute injury, and the role of metabolism is not well understood. Here, we determined the myocard...
| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Wiley
2018
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/49461/ |