Synthetic glycopolymers as modulators of protein aggregation: influence of chemical composition, topology and concentration

Novel drug excipients are required to achieve stable formulations of protein drug candidates. Synthetic glycopolymers have been shown in some cases to improve protein formulation stability, although their structure function relationship remains unknown. Here we report the synthesis of linear or 4-ar...

Full description

Bibliographic Details
Main Authors: Madeira do Ó, João, Mastrotto, Francesca, Francini, Nora, Allen, Stephanie, van der Walle, Christopher, Stolnik, Snow, Mantovani, Giuseppe
Format: Article
Published: Royal Society of Chemistry 2018
Online Access:https://eprints.nottingham.ac.uk/49364/