Is tapentadol different from classical opioids?: a review of the evidence

Tapentadol is a single molecule able to deliver analgesia by two distinct mechanisms, a feature which differentiates it from many other analgesics. Pre-clinical data demonstrate two mechanisms of action: mu-opioid receptor agonist activity and noradrenaline re-uptake inhibition. From these, one may...

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Bibliographic Details
Main Authors: Langford, Richard M., Knaggs, Roger, Farquhar-Smith, Paul, Dickenson, Anthony H.
Format: Article
Published: SAGE 2016
Subjects:
Online Access:https://eprints.nottingham.ac.uk/49225/