The characterisation of genes from a genetic screen that promote invasion

Metastasis accounts for over 90% of cancer mortality. The first step of metastasis is the invasion of cancer cells into the tissue and vasculature surrounding the tumour. Despite its clinical importance, our understanding of invasion and its genetic determinants is limited. A large-scale, loss-of-fu...

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Bibliographic Details
Main Author: Taylor, Louisa
Format: Thesis (University of Nottingham only)
Language:English
Published: 2018
Online Access:https://eprints.nottingham.ac.uk/49154/