Analysis of DNA binding and translocation by the E. coli CRISPR immunity protein Cas3
Cas3 is essential for CRISPR-Cas immunity in Escherichia coli and is conserved across Class 1, type I CRISPR-Cas systems. Cas3 is a metal-dependent nuclease and ATP-dependent helicase that is required for CRISPR interference reactions, the stage of immunity in which a Cascade complex delivers crRNA...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2018
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| Online Access: | https://eprints.nottingham.ac.uk/49136/ |