Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development
TBX5 plays a critical role in heart and forelimb development. Mutations in TBX5 cause Holt-Oram syndrome, an autosomal dominant condition that affects the formation of the heart and upper - limb. Several studies have provided significant insight into the role of TBX5 in cardiogenesis; however, how...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Published: |
Elsevier
2018
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/48810/ |