A molecular signature of dormancy in CD34+CD38- acute myeloid
leukaemia cells

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A molecular signature of dormancy in CD34+CD38- acute myeloid leukaemia cells

Dormant leukaemia initiating cells in the bone marrow niche are a crucial therapeutic target for total eradication of acute myeloid leukaemia. To study this cellular subset we created and validated an in vitro model employing the cell line TF-1a, treated with Transforming Growth Factor β1 (TGFβ1) an...

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Bibliographic Details
Main Authors:	Al-Asadi, Mazin Gh., Brindle, Grace, Castellanos, Marcos, May, Sean, Mills, Ken I., Russell, Nigel, Seedhouse, Claire, Pallis, Monica
Format:	Article
Published:	Impact Journals 2017
Subjects:	AML; dormancy; gene expression profiling
Online Access:	https://eprints.nottingham.ac.uk/48721/

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