Elucidation of the monoclonal antibody 5G8-reactive, virulence-associated lipopolysaccharide epitope of haemophilus influenzae and its role in bacterial resistance to complement-mediated killing

The phase-variable locus lex2 is required for expression of a Haemophilus influenzae lipopolysaccharide (LPS) epitope of previously unknown structure. This epitope, which is reactive with monoclonal antibody (MAb) 5G8, has been associated with virulence of type b strains. When strain RM118 (from the...

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Bibliographic Details
Main Authors: Griffin, R., Cox, Andrew D., Makepeace, Katherine, Richards, J.C., Moxon, E. Richard, Hood, Derek W.
Format: Article
Published: ASM Press 2005
Online Access:https://eprints.nottingham.ac.uk/48700/