The role of apolipoprotein N-acyl transferase, Lnt, in the lipidation of factor H binding protein of Neisseria meningitidis strain MC58 and its potential as a drug target

BACKGROUND AND PURPOSE The level of cell surface expression of the meningococcal vaccine antigen, Factor H binding protein (FHbp) varies between and within strains and this limits the breadth of strains that can be targeted by FHbp-based vaccines. The molecular pathway controlling expression of F...

Full description

Bibliographic Details
Main Authors: da Silva, R.A.G., Churchward, C.P., Karlyshev, A.V., Eleftheriadou, O., Snabaitis, A.K., Longman, M.R., Ryan, A., Griffin, R.
Format: Article
Published: Wiley 2017
Online Access:https://eprints.nottingham.ac.uk/48687/