Deubiquitination of ELK-1 by USP17 regulates its transcriptional potency and cell proliferation

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Deubiquitination of ELK-1 by USP17 regulates its transcriptional potency and cell proliferation

The transcription factor ELK-1 is associated with numerous cellular processes, notably in cell proliferation and lineage determination. ELK-1 forms a ternary complex with a dimer of Serum Response Factor at Serum Response Elements associated with immediate-early genes, such as CFOS. Following mitoge...

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Bibliographic Details
Main Author:	Ducker, Charles
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2018
Online Access:	https://eprints.nottingham.ac.uk/48595/

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