Deubiquitination of ELK-1 by USP17 regulates its transcriptional potency and cell proliferation
The transcription factor ELK-1 is associated with numerous cellular processes, notably in cell proliferation and lineage determination. ELK-1 forms a ternary complex with a dimer of Serum Response Factor at Serum Response Elements associated with immediate-early genes, such as CFOS. Following mitoge...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2018
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| Online Access: | https://eprints.nottingham.ac.uk/48595/ |