Whole-exome sequencing of the BDR cohort: evidence to support the role of the PILRA gene in Alzheimer’s disease

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Whole-exome sequencing of the BDR cohort: evidence to support the role of the PILRA gene in Alzheimer’s disease

Aim: Late-onset Alzheimer’s disease (LOAD) accounts for 95% of all Alzheimer’s cases and is genetically complex in nature. Overlapping clinical and neuropathological features between AD, FTD and Parkinson’s disease highlight the potential role of genetic pleiotropy across diseases. Recent GWAS have...

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Bibliographic Details
Main Authors:	Patel, Tulsi, Brookes, Keeley J., Turton, James, Chaudhury, Sultan, Guetta-Baranes, Tamar, Guerreiro, Rita, Bras, Jose, Hernandez, Dena, Singleton, Andrew, Francis, Paul T., Hardy, John, Morgan, Kevin
Format:	Article
Published:	Wiley 2017
Subjects:	Whole-exome sequencing Alzheimer's disease burden analysis polygenic risk score
Online Access:	https://eprints.nottingham.ac.uk/48334/

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