Whole-exome sequencing of the BDR cohort: evidence to support the role of the PILRA gene in Alzheimer’s disease

Whole-exome sequencing of the BDR cohort: evidence to support the role of the PILRA gene in Alzheimer’s disease

Aim: Late-onset Alzheimer’s disease (LOAD) accounts for 95% of all Alzheimer’s cases and is genetically complex in nature. Overlapping clinical and neuropathological features between AD, FTD and Parkinson’s disease highlight the potential role of genetic pleiotropy across diseases. Recent GWAS have...

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Bibliographic Details
Main Authors: Patel, Tulsi, Brookes, Keeley J., Turton, James, Chaudhury, Sultan, Guetta-Baranes, Tamar, Guerreiro, Rita, Bras, Jose, Hernandez, Dena, Singleton, Andrew, Francis, Paul T., Hardy, John, Morgan, Kevin
Format: Article
Published: Wiley 2017
Subjects:
Whole-exome sequencing
Alzheimer's disease
burden analysis
polygenic risk score
Online Access:https://eprints.nottingham.ac.uk/48334/

Internet

https://eprints.nottingham.ac.uk/48334/

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