Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography

QR Code

Obesity and type 2 diabetes are important risk factors underlying previously undiagnosed cirrhosis in general practice: a cross-sectional study using Transient Elastography

Background: Rising cirrhosis incidence and mortality in the United Kingdom has been attributed predominantly to excess alcohol consumption. However, metabolic risk factors such as type 2 diabetes and obesity may also be important. Aim: To screen at-risk individuals in general practice for undetecte...

Full description

Bibliographic Details
Main Authors:	Harman, David J., Ryder, Stephen D., James, Martin W., Wilkes, Emilie A., Card, Timothy R., Aithal, Guruprasad P., Guha, Indra Neil
Format:	Article
Published:	Wiley 2018
Subjects:	Alcohol-related liver disease cirrhosis liver fibrosis liver function tests non-alcoholic fatty liver disease
Online Access:	https://eprints.nottingham.ac.uk/48325/

Similar Items

The identification of chronic liver disease in primary care using non-invasive diagnostics within a novel pathway
by: Harman, David J.
Published: (2017)

Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data
by: Otete, Harmony E., et al.
Published: (2018)

Cholesteryl ester transfer protein gene ploymorphisms increase the risk of fatty liver in females independent of adisposity
by: Adams, L., et al.
Published: (2012)

Liver cirrhosis in England--an observational study: are we measuring its burden occurrence correctly?
by: Ratib, Sonia, et al.
Published: (2017)

Low serum 25-hydroxyvitamin D concentrations are associated with non-alcoholic fatty liver disease in adolescents independent of adiposity
by: Black, Lucinda, et al.
Published: (2014)

Assessment of dietary factors in patients with nonalcoholic fatty liver disease and an intervention study to investigate the effects of low glycaemic index diet
by: Al-Awadi, Amina
Published: (2023)

Using non-invasive biomarkers to identify hepatic fibrosis in people with type 2 diabetes mellitus: the Edinburgh type 2 diabetes study
by: Morling, Joanne R., et al.
Published: (2014)

Increased liver fat and glycogen stores after consumption of high versus low glycaemic index food: a randomized crossover study
by: Bawden, Stephen, et al.
Published: (2016)

Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study
by: Otete, Harmony E., et al.
Published: (2016)

Iron and Hepatic Carcinogenesis
by: Tirnitz-Parker, Janina, et al.
Published: (2013)

Detection of liver injury in IBD using Transient Elastography
by: Thin, L., et al.
Published: (2014)

Cloning, Expression and Characterization of Hepatitis B Large Surface Antigen In Yeast System
by: Mohamad Sinang, Fazia
Published: (2010)

Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review
by: Harris, Rebecca, et al.
Published: (2017)

Exploring the experience of people at-risk of Non-alcoholic Fatty Liver Disease in making and maintaining lifestyle changes
by: Mehta, Rhian Mehta
Published: (2024)

Modelling non-alcoholic fatty liver disease (NAFLD) using human induced pluripotent stem cell (hiPSC)-derived hepatocytes
by: Lo, Peggy Cho Kiu
Published: (2022)

Role of TWEAK in coregulating liver progenitor cell and fibrogenic responses
by: Tirnitz-Parker, Nina, et al.
Published: (2014)

Biomarkers to predict advanced liver diseases
by: Alenezi, Yusef
Published: (2024)

Elucidating feline hepatic lipidosis through serum biochemistry, histopathology and gene expression in the Klang valley stray cats
by: Salleh, Muhammad Fadzly
Published: (2020)

The effect of exercise training on intrahepatic triglyceride and hepatic insulin sensitivity: a systematic review and meta-analysis
by: Sargeant, Jack A., et al.
Published: (2018)

Comparison of hepatoma cell lines and primary human hepatocytes as models to study the development of hepatic steatosis
by: Huggett, Zoe
Published: (2020)

ADAPT: an algorithm incorporating PRO-C3 accurately identifies patients with NAFLD and advanced fibrosis
by: Daniels, Samuel J., et al.
Published: (2018)

MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C
by: Thabet, Khaled, et al.
Published: (2016)

The histomorphological analysis of liver following administration of low doses of diclofenac and ibuprofen
by: Mohanambal, Moorthy, et al.
Published: (2009)

The effect of circulatory dysfunction upon the liver in haemodialysis patients
by: Grant, Claire
Published: (2019)

The role of ethnicity in the increased susceptibility to non-alcoholic fatty liver disease in people of Indian origin
by: Chalmers, Jane
Published: (2021)

Formation, morphology and function of a 3D hepatocyte-hepatic stellate cell co-culture system
by: Thomas, Robert James
Published: (2006)

Transcriptomic analysis of mouse liver reveals a potential hepato-enteric pathogenic mechanism in acute Toxoplasma gondii infection
by: He, Jun-Jun, et al.
Published: (2016)

A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis
by: Friedman, Scott L., et al.
Published: (2018)

SOX9 predicts progression towards cirrhosis in patients while its loss protects against liver fibrosis
by: Athwal, Varinder S., et al.
Published: (2017)

Lower Fructose Intake May Help Protect Against Development of Nonalcoholic Fatty Liver in Adolescents With Obesity
by: O'Sullivan, T., et al.
Published: (2014)

The effect of pretreatment of zerumbone on fatty liver following ethanol induced Hepatotoxicity
by: Fakurazi, Sharida, et al.
Published: (2008)

Cytotoxic Effect of Girinimbine on HepG2 Cells
by: Mohan, Suvita Syam
Published: (2011)

Isoaspartate, Carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury
by: Carter, Wayne, et al.
Published: (2016)

Alcohol use disorder epidemiology and interventions to support behaviour change
by: Subhani, Mohsan
Published: (2023)

Mechanism-based intervention in Non-Alcoholic Fatty Liver Disease: mapping the muscle-liver axis and exploring the effect of L-carnitine on liver fat, insulin sensitivity and mitochondrial energy kinetics
by: Thiagarajan, Prarthana
Published: (2021)

The role of intramyocellular lipid content in the physiological changes observed in inactivity, exercise, and non-alcoholic fatty liver disease
by: Chivaka, Prince
Published: (2023)

Hepatoprotective activity of Dicranopteris linearis (Burm. f.) Underw. leaf methanol extract and its ethyl acetate fraction
by: Kamisan, Farah Hidayah
Published: (2017)

Microsphere distribution and radiation dosimetry in human liver following Yttrium-90 microsphere therapy.
by: Campbell, Andrew M.
Published: (2000)

Antifibrotic Effect of Transforming Growth Factor Beta 1 Inhibitor Extract from Streptomyces SP.Strain H6552 on Human Hepatic Stellate Cells
by: Lim, Chooi Ling
Published: (2010)

Characterization of human stem cell-derived hepatocytes
by: Abukunna, Fatima
Published: (2018)