Linifanib – a multi-targeted receptor tyrosine kinase inhibitor and a low molecular weight gelator

In this study we demonstrate that linifanib, a multi-targeted receptor tyrosine kinase inhibitor, with a key urea containing pharmacophore, self-assembles into a hydrogel in the presence of low amounts of solvent. We demonstrate the role of the urea functional group and that of fluorine substitution...

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Bibliographic Details
Main Authors: Marlow, Maria, Al-Ameedee, Mohammed, Smith, Thomas, Wheeler, Simon, Stocks, Michael J.
Format: Article
Published: Royal Society of Chemistry 2015
Online Access:https://eprints.nottingham.ac.uk/48294/