Calculating polygenic risk score for individuals with sporadic early onset Alzheimer’s disease
Sporadic early onset Alzheimer’s disease (sEOAD) exhibits the symptoms of late onset Alzheimer’s disease (LOAD) but lacks the familial aspect of the early onset familial form. The genetics of Alzheimer’s disease (AD) identifies the APOE ε4 allele to be the greatest risk factor; however, it is a comp...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2017
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| Online Access: | https://eprints.nottingham.ac.uk/48025/ |