Biochemical analysis of Hel308 and HelQ helicases

DNA replication is an essential process conducted by the replisome. This large protein complex is continually challenged by DNA insults which hamper progression resulting in replication fork stalling or collapse. Paused replication forks contribute to a state of genome instability which is a major h...

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Bibliographic Details
Main Author: Buckley, Ryan J.
Format: Thesis (University of Nottingham only)
Language:English
Published: 2017
Online Access:https://eprints.nottingham.ac.uk/47926/