MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancer

MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancer

Background: Altered cellular metabolism is a hallmark of cancer and some are reliant on Glutamine for sustained proliferation and survival. We hypothesise that the Glutamine-Proline regulatory axis has a key role in Breast cancer (BC) in the highly proliferative classes. Methods: Glutaminase (GLS),...

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Bibliographic Details
Main Authors: Craze, Madeleine L., Cheung, Hayley, Jewa, Natasha, Coimbra, Nuno D.M., Soria, Daniele, El-Ansari, Rokaya, Aleskandarany, Mohammed A., Cheng, Kiu Wai, Diez-Rodriguez, Maria, Nolan, Christopher C., Ellis, Ian O., Rakha, Emad, Green, Andrew R.
Format: Article
Published: Cancer Research UK 2017
Subjects:
metabolism
breast cancer
prognosis
Luminal B
glutamine
proline
Online Access:https://eprints.nottingham.ac.uk/47502/

Internet

https://eprints.nottingham.ac.uk/47502/

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