Synthesis and characterisation of multi-substituted hydroxyapatites
This thesis presents a range of novel mono and di-substituted hydroxyapatite powders, characterised by a range of techniques to ascertain their chemical composition, crystallographic composition, physical properties, and in vitro bioactivity. The novel compositions consist of substituting a range...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2018
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| Online Access: | https://eprints.nottingham.ac.uk/47482/ |
| _version_ | 1848797557997699072 |
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| author | McCarthy, Benjamin P. |
| author_facet | McCarthy, Benjamin P. |
| author_sort | McCarthy, Benjamin P. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | This thesis presents a range of novel mono and di-substituted hydroxyapatite powders, characterised by a range of techniques to ascertain their chemical composition, crystallographic composition, physical properties, and in vitro bioactivity.
The novel compositions consist of substituting a range of Borate, Sulphate, Silicate, and Strontium in levels ranging from 1.5 mol.%, up to 5 mol.%. It was found that a 4 mol.% inclusion of 2 mol.% Sr2+ and 2 mol.% SO42- gave a significant increase in the amount of osteocalcin produced and may represent an improved biomaterial warranting further study. |
| first_indexed | 2025-11-14T20:05:47Z |
| format | Thesis (University of Nottingham only) |
| id | nottingham-47482 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T20:05:47Z |
| publishDate | 2018 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-474822025-02-28T13:53:45Z https://eprints.nottingham.ac.uk/47482/ Synthesis and characterisation of multi-substituted hydroxyapatites McCarthy, Benjamin P. This thesis presents a range of novel mono and di-substituted hydroxyapatite powders, characterised by a range of techniques to ascertain their chemical composition, crystallographic composition, physical properties, and in vitro bioactivity. The novel compositions consist of substituting a range of Borate, Sulphate, Silicate, and Strontium in levels ranging from 1.5 mol.%, up to 5 mol.%. It was found that a 4 mol.% inclusion of 2 mol.% Sr2+ and 2 mol.% SO42- gave a significant increase in the amount of osteocalcin produced and may represent an improved biomaterial warranting further study. 2018-07-13 Thesis (University of Nottingham only) NonPeerReviewed application/pdf en arr https://eprints.nottingham.ac.uk/47482/1/Ben%20McCarthy%20Final%20Corrections%20Thesis%20%2819.09.17%29%20edited%20dedication.pdf McCarthy, Benjamin P. (2018) Synthesis and characterisation of multi-substituted hydroxyapatites. PhD thesis, University of Nottingham. Hydroxyapatite; Implants Artificial |
| spellingShingle | Hydroxyapatite; Implants Artificial McCarthy, Benjamin P. Synthesis and characterisation of multi-substituted hydroxyapatites |
| title | Synthesis and characterisation of multi-substituted hydroxyapatites |
| title_full | Synthesis and characterisation of multi-substituted hydroxyapatites |
| title_fullStr | Synthesis and characterisation of multi-substituted hydroxyapatites |
| title_full_unstemmed | Synthesis and characterisation of multi-substituted hydroxyapatites |
| title_short | Synthesis and characterisation of multi-substituted hydroxyapatites |
| title_sort | synthesis and characterisation of multi-substituted hydroxyapatites |
| topic | Hydroxyapatite; Implants Artificial |
| url | https://eprints.nottingham.ac.uk/47482/ |