Stemness and chemoresistance in epithelial ovarian carcinoma cells under shear stress

One of greatest challenges to the successful treatment of cancer is drug resistance. An exciting approach is the eradication of cancer stem cells (CSCs). However, little is known about key signals regulating the formation and expansion of CSCs. Moreover, lack of a reliable predictive preclinical mod...

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Bibliographic Details
Main Authors: Ip, Carman K.M., Li, Shan-Shan, Tang, Matthew Y.H., Sy, Samuel K.H., Ren, Yong, Shum, Ho Cheung, Wong, Alice S.T.
Format: Article
Published: Nature Publishing Group 2016
Online Access:https://eprints.nottingham.ac.uk/47329/