Assessment of DNA damage and DNA damage response and repair in dormancy-enriched leukemia cells

Acute myeloid leukaemia (AML) is a heterogeneous myeloid malignancy characterized by clonal expansion of abnormal/immature hematopoietic precursor cells in the bone marrow. A side compartment in the BM niche consists of abnormal, quiescent cells, which are called dormant leukemic initiating cells (D...

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Bibliographic Details
Main Author: Aldosari, Sahar
Format: Thesis (University of Nottingham only)
Language:English
Published: 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/47257/