Manganese exposure: linking down-regulation of miRNA-7 and miRNA-433 with α-synuclein overexpression and risk of idiopathic Parkinson's disease

Manganese exposure: linking down-regulation of miRNA-7 and miRNA-433 with α-synuclein overexpression and risk of idiopathic Parkinson's disease

Manganese is an essential trace element however elevated environmental and occupational exposure to this element has been correlated with neurotoxicity symptoms clinically identical to idiopathic Parkinson's disease. In the present study we chronically exposed human neuroblastoma SH-SY5Y cells...

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Bibliographic Details
Main Authors: Tarale, Prashant, Daiwile, Atul P., Sivanesan, Saravanadevi, Stöger, Reinhard, Bafana, Amit, Naoghare, Pravin K., Parmar, Devendra, Chakrabarti, Tapan, Krishnamurthi, Kannan
Format: Article
Published: Elsevier 2018
Subjects:
Manganese; SH-SY5Y; miRNA; SNCA; Parkinson's disease
Online Access:https://eprints.nottingham.ac.uk/47102/

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https://eprints.nottingham.ac.uk/47102/

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