Stabilization of angiotensin-(1-7) by key substitution with a cyclic non-natural amino acid

Angiotensin-(1-7) [Ang-(1-7)], a heptapeptide hormone of the renin-angiotensin-aldosterone system (RAAS), is a promising candidate as a treatment for cancer that reflects its antiproliferative and anti-angiogenic properties. However, the peptide’s therapeutic potential is limited by the short half-l...

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Bibliographic Details
Main Authors: Wester, Anita, Devocelle, Marc, Tallant, E. Ann, Chappell, Mark C., Gallagher, Patricia E., Paradisi, Francesca
Format: Article
Published: Springer 2017
Online Access:https://eprints.nottingham.ac.uk/47022/