1,4-addition of TMSCCl3to nitroalkenes: efficient reaction conditions and mechanistic understanding

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1,4-addition of TMSCCl3to nitroalkenes: efficient reaction conditions and mechanistic understanding

Improved synthetic conditions allow preparation of TMSCCl3 in good yield (70 %) and excellent purity. Compounds of the type NBu4X [X=Ph3SiF2 (TBAT), F (tetrabutylammonium fluoride, TBAF), OAc, Cl and Br] act as catalytic promoters for 1,4-additions to a range of cyclic and acyclic nitroalkenes, in T...

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Bibliographic Details
Main Authors:	Wu, Na, Wahl, Benoit, Woodward, Simon, Lewis, William
Format:	Article
Published:	Wiley-VCH Verlag 2014
Subjects:	brønsted base catalysis; catalysis; Michael addition; reaction mechanisms; trichloromethylation
Online Access:	https://eprints.nottingham.ac.uk/46650/

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