Influence of 1α, 25-dihydroxyvitamin D3 [1, 25(OH)2D3] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes

QR Code

Influence of 1α, 25-dihydroxyvitamin D3 [1, 25(OH)2D3] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes

Background Sox 9 is a major marker of chondrocyte differentiation. When chondrocytes are cultured in vitro they progressively de-differentiate and this is associated with a decline in Sox 9 expression. The active form of vitamin D, 1, 25 (OH)2D3 has been shown to be protective of cartilage in b...

Full description

Bibliographic Details
Main Authors:	Hdud, Ismail M., Loughna, Paul
Format:	Article
Published:	BioMed Central 2014
Subjects:	Cartilage Vitamin D Sox 9 TRPV Chondrocyte
Online Access:	https://eprints.nottingham.ac.uk/46623/

Similar Items

Effects of cyclic equibiaxial mechanical stretch on α-BK and TRPV4 expression in equine chondrocytes
by: Hdud, Ismail M., et al.
Published: (2014)

Dedifferentiation and redifferentiation of canine articular chondrocytes
by: Penny, Jasmine Rachel
Published: (2015)

Effect of osmotic stress on the expression of TRPV4 and BKCa channels and possible interaction with ERK1/2 and p38 in cultured equine chondrocytes
by: Hdud, Ismail M., et al.
Published: (2014)

Expression of transient receptor potential vanilloid (TRPV) channels in different passages of articular chondrocytes
by: Hdud, Ismail M., et al.
Published: (2012)

Study of morphologic response of chondrocytes to uniaxial compression of articular cartilage
by: Wu, Ping, et al.
Published: (2008)

Expression of a SOX1 overlapping transcript in neural differentiation and cancer models
by: Azaz, Ahmad, et al.
Published: (2017)

3D bioprinting for potential use in nasal cartilage reconstruction
by: Ruiz Cantu, Laura A.
Published: (2018)

Analysis of SOX1 regulation in stem cell and cancerous cell lines
by: Ahmad, Azaz
Published: (2017)

SUMOylation of Sox2 in neural stem cells
by: Marelli, Elisa
Published: (2018)

A comparison of the responsiveness of 4 commonly used patient-reported outcome instruments at 5 years after matrix-induced autologous chondrocyte implantation
by: Ebert, J., et al.
Published: (2013)

Articular cartilage morphology and synovial fluid protein biomarkers in the monosodium iodoacetate-induced osteoarthritis rabbit model
by: Tan, Wei Miao @ Rachel
Published: (2017)

SUMOylation as a regulatory mechanism for the Sox3 transcription factor
by: Alfassam, Haifa
Published: (2019)

Cartilaginous markers expression in human articular chondrocytes overexpressed with SOX9 gene
by: Mohamad Sukri, Norhamiza, et al.
Published: (2014)

Replacement of degraded articular cartilage using stem cell-based therapy in rabbit model of osteoarthritis
by: M. Abofila, Marwan Taher
Published: (2012)

Determination of vitamin D levels in food samples and effect of calcium on regulation of vitamin D absorption
by: Osman, Nurul Nadiah
Published: (2018)

Characterization of a Sulfuramino Acid Lyase from Citrobacter Freundii (KP25)
by: Lim, Leng Choo
Published: (2003)

Texture analysis of the 3D collagen network and automatic classification of the physiology of articular cartilage
by: Duan, X., et al.
Published: (2014)

Effects of resveratrol, piceatannol and quercetin in an equine cartilage explant model for potential use in treating osteoarthritis
by: Islam, Purba
Published: (2019)

DNA methylation analysis of Sox2 regulatory regions SRR1 and SRR2 in undifferentiated and differentiated mouse embryonic stem cells
by: Batool, Sajida
Published: (2013)

The Consequences of the SOX Ripple Effect on the UK
by: Bovey, Richard
Published: (2006)

Factors predictive of outcome 5 years after matrix-induced autologous chondrocyte implantation in the tibiofemoral joint
by: Ebert, J., et al.
Published: (2013)

Benzamil sensitive ion channels contribute to volume regulation in canine chondrocytes
by: Lewis, R., et al.
Published: (2013)

SOX9 predicts progression towards cirrhosis in patients while its loss protects against liver fibrosis
by: Athwal, Varinder S., et al.
Published: (2017)

Effects of ageing and vitamin D deficiency on vitamin D receptor (VDR) expression in human skeletal muscle
by: Ong, Terence
Published: (2015)

The progression of isokinetic knee strength after matrix-induced autologous chondrocyte implantation: implications for rehabilitation and return to activity
by: Ebert, J., et al.
Published: (2014)

Identifying the potential of transcription factor Sox9 gene transfer in chondrocytes differentiation and articular cartilage formation in vitro
by: Mohamad Sukri, Norhamiza, et al.
Published: (2015)

Chondrocytes-induced SOX5/6/9 and TERT genes for articular cartilage tissue engineering: hype or hope?
by: Md Ali @ Tahir, Aisyah Hanani, et al.
Published: (2017)

Sox-9 transient transfection enhances chondrogenic expression of osteoarthritic human articular chondrocytes in vitro: preliminary analysis
by: Sha'ban, Munirah, et al.
Published: (2011)

Serum 25-hydroxyvitamin D is associated with reduced verbal episodic memory in healthy, middle-aged and older adults
by: Lam, Virginie, et al.
Published: (2015)

Association of T2 mapping of knee cartilage with age, gender & BMI among young adults attending Pusat Pengimejan Diagnostik Nucklear (PPDN), Universiti Putra Malaysia
by: Soo, Tze Hui
Published: (2021)

Diabetic neuropathy: a mechanism of TRPV1 sensitisation and the treatment with Vascular Endothelial Growth Factor-A165b (VEGF-A165b)
by: Bestall, Samuel
Published: (2017)

Rotated hough filtering for automatically distinguishing the collagen bundles in the most superficial layer of articular cartilage
by: Duan, Xiaojuan, et al.
Published: (2013)

25-hydroxyvitamin D3 status is associated with developing adaptive and innate immune responses in the first 6 months of life
by: Jones, A., et al.
Published: (2015)

Elastin fibers display a versatile microfibril network in articular cartilage depending on the mechanical microenvironments
by: He, Bo, et al.
Published: (2013)

Quantitative stereophotogrammetric & MRI evaluation of ankle articular cartilage and ankle joint contact characteristics
by: Millington, Steven Andrew
Published: (2008)

Utilizing confocal microscopy to measure refractive index of articular cartilage
by: Wang, K., et al.
Published: (2012)

The role of the vitamin D axis in skeletal muscle physiology: a multi-modal approach
by: Bollen, Shelby
Published: (2024)

Depth-dependent refractive index of normal and early degenerated articular cartilage
by: Wang, K., et al.
Published: (2013)

Role of vitamin D and E in modulating glucose uptake and insulin sensitivity in insulin-resistant neuronal cells
by: Zaulkffali, Amirah Salwani
Published: (2017)

Correlation between clinical and radiological outcomes after matrix-induced autologous chondrocyte implantation in the femoral condyles
by: Ebert, J., et al.
Published: (2014)