Influence of 1α, 25-dihydroxyvitamin D3 [1, 25(OH)2D3] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes
Background Sox 9 is a major marker of chondrocyte differentiation. When chondrocytes are cultured in vitro they progressively de-differentiate and this is associated with a decline in Sox 9 expression. The active form of vitamin D, 1, 25 (OH)2D3 has been shown to be protective of cartilage in b...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Published: |
BioMed Central
2014
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/46623/ |