Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma

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Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma

Obstructive lung diseases are common causes of disability and death worldwide. A hallmark feature is aberrant activation of Gq protein–dependent signaling cascades. Currently, drugs targeting single G protein (heterotrimeric guanine nucleotide–binding protein)–coupled receptors (GPCRs) are used to r...

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Bibliographic Details
Main Authors:	Matthey, Michaela, Roberts, Richard, Seidinger, Alexander, Simon, Annika, Schröder, Ralf, Kuschak, Markus, Annala, Suvi, König, Gabriele M., Müller, Christa E., Hall, Ian P., Kostenis, Evi, Wenzel, Daniela
Format:	Article
Published:	American Association for the Advancement of Science 2017
Online Access:	https://eprints.nottingham.ac.uk/46589/

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