Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma
Obstructive lung diseases are common causes of disability and death worldwide. A hallmark feature is aberrant activation of Gq protein–dependent signaling cascades. Currently, drugs targeting single G protein (heterotrimeric guanine nucleotide–binding protein)–coupled receptors (GPCRs) are used to r...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Published: |
American Association for the Advancement of Science
2017
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| Online Access: | https://eprints.nottingham.ac.uk/46589/ |