Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana
Amphotericin B has emerged as the therapy of choice for use against the leishmaniases. Administration of the drug in its liposomal formulation as a single injection is being promoted in a campaign to bring the leishmaniases under control. Understanding the risks and mechanisms of resistance is there...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Published: |
Public Library of Science
2017
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| Online Access: | https://eprints.nottingham.ac.uk/45552/ |