Lipid components of bile increase the protective effect of conjugated bile salts against antifungal drugs

Fungi and bacteria can persist in the human gall bladder. Previous studies have shown that bile protects Candida albicans in this cryptic host niche from antifungals, providing a reservoir for intestinal re-colonization after discontinuation of antifungal therapy. Bile and conjugated bile salts trap...

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Bibliographic Details
Main Authors: Hsieh, Shih-Hung, Brock, Matthias
Format: Article
Published: Elsevier 2017
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Online Access:https://eprints.nottingham.ac.uk/45544/