Kinetic analysis of Copper(I)/Feringa-Phosphoramidite Catalysed AlEt3 1,4-Addition to Cyclohex-2-en-1-one
ReactIR studies of mixtures of AlEt3 (A) and cyclohex-2-en-1-one (CX) in Et2O indicate immediate formation of the Lewis acid-base complex (CX.A) at -40 oC (K = 12.0 M-1, ΔGoreact -1.1 kcal mol-1). Copper(I) catalysts, derived from pre-catalytic Cu(OAc)2 (up to 5 mol-%) and (R,S,S)-P(binaphtholate){N...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
American Chemical Society
2017
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/45536/ |