Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation
When blood is exposed to variety of artificial surfaces and biologic substances, the plasma proteins factor XII (FXII) and prekallikrein undergo reciprocal proteolytic conversion to the proteases αFXIIa and α-kallikrein by a process called contact activation. These enzymes contribute to host-defense...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Published: |
American Society of Hematology
2017
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| Online Access: | https://eprints.nottingham.ac.uk/44922/ |