A refined method to study gene dosage changes in-vitro using CRISPR/Cas9
Aims: Gene dosage can have a major impact on cell biology although, hitherto, is has been difficult to study using in-vitro models. We sought to refine and accelerate the development of “gene dosage” models through using CRISPR/Cas9 (a gene-editing technology) for sequential knockout of gene alleles...
| Main Authors: | , , |
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| Format: | Article |
| Published: |
BMJ Publishing Group Ltd
2017
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| Online Access: | https://eprints.nottingham.ac.uk/44871/ |