Investigating the biochemical properties of two Nanog orthologues identified in the axolotl

Pluripotent cells give rise to the germ line and the soma. The expression of the Nanog orthologue axNanog is required to establish pluripotency during axolotl development and has a conserved role interacting with axSMAD2 and DPY30 to deposit H3K4me3 through COMPASS. Transcriptome analysis has reveal...

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Bibliographic Details
Main Author: Simpson, Luke A.
Format: Thesis (University of Nottingham only)
Language:English
Published: 2017
Online Access:https://eprints.nottingham.ac.uk/44738/