Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review
Background: The complex management for patients presenting to hospital with vertebral fragility fractures provides justification for the development of specific services for them. A systematic review was undertaken to determine the incidence of hospital admission, patient characteristics, and health...
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| Format: | Article |
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Oxford University Press
2018
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| Online Access: | https://eprints.nottingham.ac.uk/44712/ |
| _version_ | 1848796980941160448 |
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| author | Ong, Terence Kantachuvesiri, Pitchayud Sahota, Opinder Gladman, John R.F. |
| author_facet | Ong, Terence Kantachuvesiri, Pitchayud Sahota, Opinder Gladman, John R.F. |
| author_sort | Ong, Terence |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background: The complex management for patients presenting to hospital with vertebral fragility fractures provides justification for the development of specific services for them. A systematic review was undertaken to determine the incidence of hospital admission, patient characteristics, and health outcomes of vertebral fragility fracture patients to inform the development of such a service.
Methods: Non-randomised studies of vertebral fragility fracture in hospital were included. Searches were conducted using electronic databases and citation searching of the included papers.
Results: 19 studies were included. The incidence of hospital admission varied from 2.8-19.3 per 10,000/year. The average patient age was 81 years, the majority having presented with a fall. A diagnosis of osteoporosis or previous fragility fracture was reported in around one third of patients. Most patients (75% men and 78% women) had five or more co-pathologies. Most patients were managed non-operatively with a median hospital length of stay of 10 days. One third of patients were started on osteoporosis treatment. Inpatient and one year mortality was between 0.9-3.5%, and 20–25% respectively: between 34-50% were discharged from hospital to a care facility. Many patients were more dependent with activities of daily living on discharge compared to their pre-admission level. Older age and increasing comorbidities was associated with longer hospital stay and higher mortality.
Conclusion: These findings indicate that specific hospital services for patients with vertebral fragility fractures should take into consideration local hospitalisation rates for the condition, and should be multifaceted - providing access to diagnostic, therapeutic, surgical and rehabilitation interventions. |
| first_indexed | 2025-11-14T19:56:36Z |
| format | Article |
| id | nottingham-44712 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:56:36Z |
| publishDate | 2018 |
| publisher | Oxford University Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-447122020-05-04T19:24:38Z https://eprints.nottingham.ac.uk/44712/ Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review Ong, Terence Kantachuvesiri, Pitchayud Sahota, Opinder Gladman, John R.F. Background: The complex management for patients presenting to hospital with vertebral fragility fractures provides justification for the development of specific services for them. A systematic review was undertaken to determine the incidence of hospital admission, patient characteristics, and health outcomes of vertebral fragility fracture patients to inform the development of such a service. Methods: Non-randomised studies of vertebral fragility fracture in hospital were included. Searches were conducted using electronic databases and citation searching of the included papers. Results: 19 studies were included. The incidence of hospital admission varied from 2.8-19.3 per 10,000/year. The average patient age was 81 years, the majority having presented with a fall. A diagnosis of osteoporosis or previous fragility fracture was reported in around one third of patients. Most patients (75% men and 78% women) had five or more co-pathologies. Most patients were managed non-operatively with a median hospital length of stay of 10 days. One third of patients were started on osteoporosis treatment. Inpatient and one year mortality was between 0.9-3.5%, and 20–25% respectively: between 34-50% were discharged from hospital to a care facility. Many patients were more dependent with activities of daily living on discharge compared to their pre-admission level. Older age and increasing comorbidities was associated with longer hospital stay and higher mortality. Conclusion: These findings indicate that specific hospital services for patients with vertebral fragility fractures should take into consideration local hospitalisation rates for the condition, and should be multifaceted - providing access to diagnostic, therapeutic, surgical and rehabilitation interventions. Oxford University Press 2018-01-01 Article PeerReviewed Ong, Terence, Kantachuvesiri, Pitchayud, Sahota, Opinder and Gladman, John R.F. (2018) Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review. Age and Ageing, 47 (1). pp. 17-25. ISSN 1468-2834 vertebral fragility fracture hospital osteoporosis older people https://academic.oup.com/ageing/article-lookup/doi/10.1093/ageing/afx079 doi:10.1093/ageing/afx079 doi:10.1093/ageing/afx079 |
| spellingShingle | vertebral fragility fracture hospital osteoporosis older people Ong, Terence Kantachuvesiri, Pitchayud Sahota, Opinder Gladman, John R.F. Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review |
| title | Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review |
| title_full | Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review |
| title_fullStr | Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review |
| title_full_unstemmed | Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review |
| title_short | Characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review |
| title_sort | characteristics and outcomes of hospitalised patients with vertebral fragility fractures: a systematic review |
| topic | vertebral fragility fracture hospital osteoporosis older people |
| url | https://eprints.nottingham.ac.uk/44712/ https://eprints.nottingham.ac.uk/44712/ https://eprints.nottingham.ac.uk/44712/ |