New perspectives on the development of extrahepatic portosystemic shunts
Objective: To develop a hypothesis for the developmental modality of extrahepatic portosystemic shunts. Methods: A retrospective review of a series of dogs and cats managed for congenital portosystemic shunts. Using these data a hypothesis for the role of preferential venous blood flow in the devel...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Published: |
Wiley
2017
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/44593/ |
| _version_ | 1848796953580666880 |
|---|---|
| author | White, Robert N. Shales, Chris Parry, Andrew |
| author_facet | White, Robert N. Shales, Chris Parry, Andrew |
| author_sort | White, Robert N. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Objective: To develop a hypothesis for the developmental modality of extrahepatic portosystemic shunts.
Methods: A retrospective review of a series of dogs and cats managed for congenital portosystemic shunts. Using these data a hypothesis for the role of preferential venous blood flow in the development of common extrahepatic PSSs was postulated. In addition, an online literature search was used to retrieve peer-reviewed data describing the detailed anatomy of shunts in dogs and cats. A systematic review of these data was used as a preliminary test of the hypothesis.
Results: In total 50 dogs and 10 cats met the inclusion criteria revealing five common and distinct shunt types. In the dog, these were spleno-caval, left gastro-phrenic, left gastro-azygos and those involving the right gastric vein. The online search confirmed that these were responsible for 94% of extrahepatic shunts described in this species. In the cat, the four shunt types observed were spleno-caval, left gastro-phrenic, left gastro-caval and left gastro-azygos. Excluding the left gastro-azygos, which from the online search was not described in the cat, the spleno-caval, left gastro-phrenic and left gastro-caval were responsible for 92% of extrahepatic shunts in this species. These data were used to develop, propose and provisionally test a hypothesis for the development of extrahepatic portosystemic shunts.
Clinical Significance: We hypothesise that it is the presence of preferential blood flow that influences the subsequent formation of one of a number of defined and consistent congenital extrahepatic portosystemic shunts in dogs and cats. |
| first_indexed | 2025-11-14T19:56:10Z |
| format | Article |
| id | nottingham-44593 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:56:10Z |
| publishDate | 2017 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-445932020-05-04T19:04:40Z https://eprints.nottingham.ac.uk/44593/ New perspectives on the development of extrahepatic portosystemic shunts White, Robert N. Shales, Chris Parry, Andrew Objective: To develop a hypothesis for the developmental modality of extrahepatic portosystemic shunts. Methods: A retrospective review of a series of dogs and cats managed for congenital portosystemic shunts. Using these data a hypothesis for the role of preferential venous blood flow in the development of common extrahepatic PSSs was postulated. In addition, an online literature search was used to retrieve peer-reviewed data describing the detailed anatomy of shunts in dogs and cats. A systematic review of these data was used as a preliminary test of the hypothesis. Results: In total 50 dogs and 10 cats met the inclusion criteria revealing five common and distinct shunt types. In the dog, these were spleno-caval, left gastro-phrenic, left gastro-azygos and those involving the right gastric vein. The online search confirmed that these were responsible for 94% of extrahepatic shunts described in this species. In the cat, the four shunt types observed were spleno-caval, left gastro-phrenic, left gastro-caval and left gastro-azygos. Excluding the left gastro-azygos, which from the online search was not described in the cat, the spleno-caval, left gastro-phrenic and left gastro-caval were responsible for 92% of extrahepatic shunts in this species. These data were used to develop, propose and provisionally test a hypothesis for the development of extrahepatic portosystemic shunts. Clinical Significance: We hypothesise that it is the presence of preferential blood flow that influences the subsequent formation of one of a number of defined and consistent congenital extrahepatic portosystemic shunts in dogs and cats. Wiley 2017-09-05 Article PeerReviewed White, Robert N., Shales, Chris and Parry, Andrew (2017) New perspectives on the development of extrahepatic portosystemic shunts. Journal of Small Animal Practice, 58 (12). pp. 669-677. ISSN 1748-5827 Soft tissue Cardiovascular Portosystemic shunt http://onlinelibrary.wiley.com/doi/10.1111/jsap.12728/abstract doi:10.1111/jsap.12728 doi:10.1111/jsap.12728 |
| spellingShingle | Soft tissue Cardiovascular Portosystemic shunt White, Robert N. Shales, Chris Parry, Andrew New perspectives on the development of extrahepatic portosystemic shunts |
| title | New perspectives on the development of extrahepatic portosystemic shunts |
| title_full | New perspectives on the development of extrahepatic portosystemic shunts |
| title_fullStr | New perspectives on the development of extrahepatic portosystemic shunts |
| title_full_unstemmed | New perspectives on the development of extrahepatic portosystemic shunts |
| title_short | New perspectives on the development of extrahepatic portosystemic shunts |
| title_sort | new perspectives on the development of extrahepatic portosystemic shunts |
| topic | Soft tissue Cardiovascular Portosystemic shunt |
| url | https://eprints.nottingham.ac.uk/44593/ https://eprints.nottingham.ac.uk/44593/ https://eprints.nottingham.ac.uk/44593/ |