A validation of the application of D2O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans

A validation of the application of D2O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans

Quantification of muscle protein synthesis (MPS) remains a cornerstone for understanding the control of muscle mass. Traditional [13C]amino acid tracer methodologies necessitate sustained bed rest and intravenous cannulation(s), restricting studies to ∼12 h, and thus cannot holistically inform on di...

Full description

Bibliographic Details
Main Authors: Wilkinson, Daniel J., Franchi, Martino V., Brook, Matthew S., Narici, Marco V., Williams, John P., Mitchell, William K., Szewczyk, Nathaniel J., Greenhaff, Paul L., Atherton, Philip J., Smith, Kenneth
Format: Article
Published: American Physiological Society 2014
Subjects:
Article Abstract MATERIALS AND METHODS RESULTS DISCUSSION GRANTS DISCLOSURES AUTHOR CONTRIBUTIONS ACKNOWLEDGMENTS REFERENCES Figures & Data Info PDF Alert me when this article is cited Alert me if a correction is posted Email Print Citation Tools Request Permissions Share View Full Page PDF Reddit logo RedditCiteULike logo CiteULikeMendeley logo MendeleyStumbleUpon logo StumbleUpon More in this TOC Section A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes Show more Innovative Methodology Related Articles Cited By... Calls for Papers Most Cited Most Read Role of Gut Microbiota and Gut-Brain and Gut-Liver Axes in Physiological Regulation of Inflammation
Energy Balance
and Metabolism. Deadline for Submission: September 30
2017 Role of Fetal Programming and Epigenetic Regulation on the Development of Endocrine and Metabolic Alterations. Deadline for Submission: September 30
2017 Browning and Beiging of Adipose Tissue
Its Role in the Regulation of Energy Homeostasis and as a Potential Target for Alleviating Metabolic Diseases. Deadline for Submission: September 30
2017 Mechanisms of Effects on Sleep Disruption on Adipocyte/Obesity Metabolism and Their Relation to Other Metabolic Disease. Deadline for Submission: September 30
2017 Metabolism and Signaling Functions of Amino Acids in the Regulation of Cell/Tissue Function in Health and Disease. Deadline for Submission: September 30
2017 Role of Adipose Tissue Nutrient/Vitamin Metabolism in Physiological and Altered Metabolic Settings. Deadline for Submission: September 30
2017 Endocannabinoids and Cannabinoid Receptors as Regulators of Endocrine Functions and Tissue Metabolism. Deadline for Submission: September 30
2017 Role of Myokines and Adipokines and Other Cross-Talk Mechanisms of Regulation of Endocrine and Metabolic Functions. Deadline for Submission: September 30
2017 Mitochondria Dysfunction in Aging and Metabolic Diseases. Deadline for Submission: September 30
2017 Featured Articles Development of a reliable
automated screening system to identify small molecules and biologics that promote human β cell regeneration Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus. Caspase-1 Deficiency Promotes High-Fat Diet-Induced Adipose Tissue Inflammation and the Development of Obesity Subjects Amino Acid and Protein Metabolism Exercise Deuterium Oxide protein synthesis skeletal muscle Deuterium Oxide protein synthesis skeletal muscle Deuterium Oxide; protein synthesis; skeletal muscle Deuterium Oxide; protein synthesis; skeletal muscle Deuterium Oxide; protein synthesis; skeletal muscle Deuterium Oxide; protein synthesis; skeletal muscle
Online Access:https://eprints.nottingham.ac.uk/44544/

Internet

https://eprints.nottingham.ac.uk/44544/

Similar Items