Hepatic caveolin-1 is enhanced in Cyp27A1/ApoE double knockout mice

Sterol 27-hydroxylase (CYP27A1) is involved in bile acid synthesis and cholesterol homoeostasis. Cyp27a1(−/−)/Apolipoprotein E(−/−) double knockout mice (DKO) fed a western diet failed to develop atherosclerosis. Caveolin-1 (CAV-1), the main component of caveolae, is associated with lipid homoeostas...

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Bibliographic Details
Main Authors: Zurkinden, Line, Mansour, Yosef, Rohrbach, Beatrice, Vogt, Bruno, Mistry, Hiten D., Escher, Genevieve
Format: Article
Published: Wiley 2016
Online Access:https://eprints.nottingham.ac.uk/44335/