Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells

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Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells

Selective targeting of cells for intracellular delivery of therapeutics represents a major challenge for pharmaceutical intervention in disease. Here we show pH triggered receptor-mediated endocytosis of nanoparticles via surface ligand exposure. Gold nanoparticles were decorated with two polymers:...

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Bibliographic Details
Main Authors:	Brazzale, C., Mastrotto, Francesca, Moody, P., Watson, P.D., Balasso, A., Malfanti, A., Mantovani, Giuseppe, Caliceti, Paolo, Alexander, Cameron, Jones, A.T., Salmaso, Stefano
Format:	Article
Published:	Royal Society of Chemistry 2017
Online Access:	https://eprints.nottingham.ac.uk/44261/

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