Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells
Selective targeting of cells for intracellular delivery of therapeutics represents a major challenge for pharmaceutical intervention in disease. Here we show pH triggered receptor-mediated endocytosis of nanoparticles via surface ligand exposure. Gold nanoparticles were decorated with two polymers:...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Published: |
Royal Society of Chemistry
2017
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| Online Access: | https://eprints.nottingham.ac.uk/44261/ |