Dually sensitive dextran-based micelles for methotrexate delivery

Temperature-sensitive polymeric micelles were prepared from dextran grafted with poly(N-isopropylacrylamide) (PNIPAAm) or polyethylene glycol methyl ether (PEGMA) via controlled radical polymerization and evaluated as delivery systems of the anticancer drug methotrexate (MTX). Polymer-grafting was c...

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Bibliographic Details
Main Authors: Blanco-Fernandez, B., Concheiro, A., Makwana, H., Fernandez-Trillo, Francisco, Alexander, Cameron, Alvarez-Lorenzo, C.
Format: Article
Published: Royal Society of Chemistry 2017
Online Access:https://eprints.nottingham.ac.uk/44129/