Muscle carnitine availability plays a central role in regulating fuel metabolism in the rodent

The body carnitine pool is primarily confined to skeletal muscle, where it regulates carbohydrate (CHO) and fat usage. Mildronate (3-(2,2,2-trimethylhydrazinium)-propionate) inhibits carnitine synthesis and tissue uptake, but the impact of carnitine depletion on whole-body fuel selection, muscle fue...

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Bibliographic Details
Main Authors: Porter, Craig, Constantin-Teodosiu, Dumitru, Constantin, Despina, Leighton, Brendan, Poucher, Simon M., Greenhaff, Paul L.
Format: Article
Published: Wiley 2017
Subjects:
Online Access:https://eprints.nottingham.ac.uk/43873/