Enantioselective nickel-catalyzed intramolecular allylic alkenylations enabled by reversible alkenylnickel E/Z isomerization
Enantioselective nickel-catalyzed arylative cyclizations of substrates containing a Z-allylic phosphate tethered to an alkyne are described. These reactions give multisubstituted chiral aza- and carbocycles, and are initiated by the addition of an arylboronic acid to the alkyne, followed by cyclizat...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Published: |
Wiley-VCH Verlag
2017
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/43683/ |